Materiaalzone 
Fietstoerisme 
Winkans
| 1 | 11.19% | |
| 2 | 10.97% | |
| 3 | 1.58% | |
| 4 | 1.55% | |
| 5 | 1.08% | |
| 6 | 1.05% | |
| 7 | 1.00% | |
| 8 | 0.85% | |
| 9 | 0.85% | |
| 10 | 0.83% |
Modelschatting op basis van renner-ratings en het etappeprofiel.
The stage was neutralized in memory of Wouter Weylandt, who passed away after a serious crash during the third stage.
| Datum | dinsdag 10 mei |
| Start |  Quarto dei Mille |
| Finish | Livorno |
| Afstand | 208.0 km |
Winkans
| 1 | 11.19% | |
| 2 | 10.97% | |
| 3 | 1.58% | |
| 4 | 1.55% | |
| 5 | 1.08% | |
| 6 | 1.05% | |
| 7 | 1.00% | |
| 8 | 0.85% | |
| 9 | 0.85% | |
| 10 | 0.83% |
Modelschatting op basis van renner-ratings en het etappeprofiel.